Burn your Hard drive and that will get rid of it. No seriously if you find a virus w/McAffe or Norton it will prompt you on what to do. But me I\'d wipe the whole drive and start over.
It might also be useful to check out your file associations. Like this,
Windows Explorer -> View -> Folder Options -> File Types tab
or in Windows 2000,
Windows Explorer -> Tools -> Folder Options -> File Types